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This methodology can be used to monitor trends and use of health services after transition to ICD-10-CM.Many millions of Americans are estimated to have chronic Kidney Disease. ConclusionsĬhildren with SCA can be accurately identified in administrative claims using this straightforward case definition. The same definition also had the highest performance in New York Medicaid (n = 2454), with a sensitivity of 94 percent and specificity of 86 percent. The case definition of ≥1 outpatient visit with a SCA-related or D571 code had the highest area under the ROC curve, with a sensitivity of 95 percent and specificity of 92 percent. Measures of performance varied, with sensitivities from 0.02 to 0.97 and specificities from 0.88 to 1.0. In Michigan Medicaid, 1597 children had ≥1 D57x claim 280 (18 percent) were diagnosed with SCA. A parallel analysis was conducted using New York State Medicaid claims and newborn screening data. Measures of performance (sensitivity, specificity, area under the ROC curve) were calculated using newborn screening results as the gold standard. Using specific SCA-related (D5700, D5701, and D5702) and nonspecific (D571) diagnosis codes, 23 SCA case definitions were applied to Michigan Medicaid claims (2016) to identify children with SCA. Medicaid administrative claims (2016) for children <18 years with potential SCA (any D57x diagnosis code) and newborn screening records from Michigan and New York State. To develop, test, and validate the performance of ICD-10-CM claims-based case definitions for identifying children with sickle cell anemia (SCA).

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